News
The Jain Lab is a key member of PETAL Consortium–a global network of clinicians, researchers, and data scientists dedicated to advancing care for T-cell lymphoma. For all the latest updates from the Jain Lab, visit the PETAL Consortium Newsroom and follow PETAL Consortium on LinkedIn for news.
June 2026

We are thrilled that our Clinical Research Coordinator Alexandra Lenart has been accepted to medical school at Michigan State University College of Osteopathic Medicine. She is grateful for her time in the lab and the entire team!
April 2026

We're excited to announce that PETAL's latest manuscript, "Innovative approaches for managing relapsed or refractory peripheral T-cell lymphoma" has been published in Expert Opinion On Pharmacotherapy.
Read MoreMarch 2026

We're proud to announce that our latest manuscript, "Allogeneic Transplant Outcomes in T-Cell Prolymphocytic Leukemia: A single-center retrospective study," has been published in Leukemia and Lymphoma.
Read More
We're excited to announce that PETAL's latest manuscript, "Clinical outcomes of mature T- and NK-cell lymphomas in hepatitis B virus positive individuals: results from the PETAL Global Consortium" has been published in Leukemia and Lymphoma.
Read MoreDecember 2025

Congratulations to Dr. Makoto Iwasaki, Co-investigator at PETAL Consortium, on being selected as a 2026 Lymphoma Research Foundation Scholar in the Lymphoma Scientific Research Mentoring Program (LSRMP). The LSRMP is a mentoring program from the Lymphoma Research Foundation (LRF). The program provides education for those pursuing lymphoma research, including training in research methods and design, statistical analysis, pathology, incorporating and interpreting correlative studies into clinical trials, and grant submission. Dr. Iwasaki is grateful for the LRF’s support of his research.

Global study finds early relapse predicts poor outcomes in patients with aggressive blood cancer
A new study led by investigators from PETAL Consortium at the Mass General Brigham Cancer Institute found that among patients who achieved a complete remission after initial chemotherapy treatment, survival was worse for those whose disease relapsed within 12 months of initial treatment, suggesting that alternative strategies are needed to benefit these patients.
Read MoreA new study led by investigators from PETAL Consortium at the Mass General Brigham Cancer Institute found that among patients who achieved a complete remission after initial chemotherapy treatment, survival was worse for those whose disease relapsed within 12 months of initial treatment, suggesting that alternative strategies are needed to benefit these patients.

Research Spotlight: Early Relapse Predicts Poor Outcomes in Aggressive Blood Cancer
In this research spotlight, learn about a global study led by Mark Sorial that examined patients with mature nodal T-cell lymphoma—a rare and aggressive blood cancer. The study found that patients whose cancer returns within 12 months have poorer survival outcomes but may benefit from earlier use of non-chemotherapy treatments. He explains how these findings help clarify differences in patient outcomes and pave the way for more personalized treatment strategies.
Read MoreIn this research spotlight, learn about a global study led by Mark Sorial that examined patients with mature nodal T-cell lymphoma—a rare and aggressive blood cancer. The study found that patients whose cancer returns within 12 months have poorer survival outcomes but may benefit from earlier use of non-chemotherapy treatments. He explains how these findings help clarify differences in patient outcomes and pave the way for more personalized treatment strategies.
November 2025

PETAL Consortium’s fourth manuscript accepted by Blood!
We’re thrilled to announce that PETAL’s fourth manuscript, “Early time-to-relapse as a survival prognosticator in mature T-cell/NK-cell lymphomas: results from the PETAL Consortium,” has been accepted for publication in Blood–the world’s leading and most widely cited journal in hematology. The paper is scheduled for publication in early December!
We’re thrilled to announce that PETAL’s fourth manuscript, “Early time-to-relapse as a survival prognosticator in mature T-cell/NK-cell lymphomas: results from the PETAL Consortium,” has been accepted for publication in Blood–the world’s leading and most widely cited journal in hematology. The paper is scheduled for publication in early December!
July 2025

Dr. Salvia Jain interviewed by Becker's Healthcare
Salvia Jain, MD, principal investigator and founder of PETAL Consortium, spoke with Becker's Healthcare about how combining the drugs duvelisib and romidepsin may offer a promising path to stem cell transplant for patients with peripheral and cutaneous T-cell lymphomas.
Read MoreSalvia Jain, MD, principal investigator and founder of PETAL Consortium, spoke with Becker's Healthcare about how combining the drugs duvelisib and romidepsin may offer a promising path to stem cell transplant for patients with peripheral and cutaneous T-cell lymphomas.
PETAL Publications

In this Q&A, meet Caroline MacVicar, former Clinical Research Coordinator for PETAL Consortium.
Caroline is an incoming first year medical student in the Army at Uniformed Services University and former Clinical Research Coordinator in the Jain Lab. She earned her bachelor's degree in Biological Sciences from Wellesley College. She was a volunteer at the Newton-Wellesley Hospital and was an undergraduate research assistant in a microbiology lab at Wellesley.
Read MoreCaroline is an incoming first year medical student in the Army at Uniformed Services University and former Clinical Research Coordinator in the Jain Lab. She earned her bachelor's degree in Biological Sciences from Wellesley College. She was a volunteer at the Newton-Wellesley Hospital and was an undergraduate research assistant in a microbiology lab at Wellesley.

In this Q&A, meet Mark Sorial, PETAL Consortium’s Investigator and Biostatistician!
Mark Sorial is an Investigator and Biostatistician at Massachusetts General Hospital. He earned his Doctor of Pharmacy degree at the Massachusetts College of Pharmacy and Health Sciences and is now completing his Masters of Public Health at the University of Massachusetts Amherst. He is currently a Clinical Pharmacist Specialist at the Dana-Farber Cancer Institute.
Read MoreMark Sorial is an Investigator and Biostatistician at Massachusetts General Hospital. He earned his Doctor of Pharmacy degree at the Massachusetts College of Pharmacy and Health Sciences and is now completing his Masters of Public Health at the University of Massachusetts Amherst. He is currently a Clinical Pharmacist Specialist at the Dana-Farber Cancer Institute.

Research Spotlight: Global Study Finds Improved Survival for Aggressive Blood Cancer with Early Use of Existing Drug Therapies
In this research spotlight, learn about Mark Sorial's recent publication on improved survival for patients with lymphoma with the use of existing drug therapies. He shares how these discoveries can improve patient care and lead to better treatment strategies.
Read MoreIn this research spotlight, learn about Mark Sorial's recent publication on improved survival for patients with lymphoma with the use of existing drug therapies. He shares how these discoveries can improve patient care and lead to better treatment strategies.

Research Spotlight: Study Demonstrates Drug
Combination is Well-Tolerated, Safe and Effective for
Patients with Aggressive Blood Cancer
In this research spotlight, learn about Josie Ford's recent publication on a novel drug combination for lymphoma. She shares how the team's findings could shape future approaches to care for patients with aggressive blood cancers.
Read MoreIn this research spotlight, learn about Josie Ford's recent publication on a novel drug combination for lymphoma. She shares how the team's findings could shape future approaches to care for patients with aggressive blood cancers.

In this QSA, meet Alexandra Lenart, PETAL
Consortium's CRC!
Alexandra Lenart is a Clinical Research Coordinator (CRC) at Massachusetts General Hospital. She earned her bachelor's degree in Economics at Wellesley College. Before joining PETAL Consortium, she was a Scrub Technician at Oral and Maxillofacial Surgery of Central New Jersey, as well as a Research Assistant in the Tetel Lab at Wellesley College.
Read MoreConsortium's CRC!
Alexandra Lenart is a Clinical Research Coordinator (CRC) at Massachusetts General Hospital. She earned her bachelor's degree in Economics at Wellesley College. Before joining PETAL Consortium, she was a Scrub Technician at Oral and Maxillofacial Surgery of Central New Jersey, as well as a Research Assistant in the Tetel Lab at Wellesley College.
We're excited to share that Josie Ford was interviewed by Blood Cancers Today about her recently published study in Blood Advances, which investigates the efficacy of the drug combination duvelisib and romidepsin in patients with rare and aggressive blood cancers.
Read MoreReal-World Data Study Led by Dr. Salvia Jain Highlights Promising Treatment
for Aggressive Blood Cancer
A new study led by PETAL investigator Dr. Salvia Jain demonstrates that a
combination of two blood cancer medications is well tolerated, safe, and effective for patients with aggressive blood cancers who do not respond to standard therapy. The research, based on real-world data, is now featured in the Mass General Brigham Newsroom.
Read Morefor Aggressive Blood Cancer
A new study led by PETAL investigator Dr. Salvia Jain demonstrates that a
combination of two blood cancer medications is well tolerated, safe, and effective for patients with aggressive blood cancers who do not respond to standard therapy. The research, based on real-world data, is now featured in the Mass General Brigham Newsroom.
June 2025

Founder and Principal investigator of the PETAL Consortium
In this Q&A, meet Dr. Salvia Jain–founder and principal investigator of PETAL Consortium–as she shares how her journey in medicine began and what inspired her to focus on blood cancer research.
Read MoreIn this Q&A, meet Dr. Salvia Jain–founder and principal investigator of PETAL Consortium–as she shares how her journey in medicine began and what inspired her to focus on blood cancer research.
This month, we welcomed three new members to the lab. Corben and Emma are our new clinical research coordinators and Riya is our new clinical research assistant. We are so excited to work with them
We also welcome our two new summer interns, Erica and Emmanuel, who will be
working for the PETAL consortium. They will be working on enhancing or expanding
PETAL's presence on social media platforms and posting content.
working for the PETAL consortium. They will be working on enhancing or expanding
PETAL's presence on social media platforms and posting content.
PETAL Publications
We are excited to share that our latest manuscript, "Real-world outcomes of duvelisib and romidepsin combination therapy in relapsed/refractory peripheral T-cell lymphomas (PTCL),"has been accepted for publication in Blood Advances. Read more on how it offers critical real-world evidence supporting a promising treatment strategy to improve outcomes and facilitate curative transplants for patients with aggressive PTCL
Read MoreMay 2025
PETAL Highlights
PETAL Consortium Featured in ASCO Post!
We are excited to share that PETAL Consortium is featured in the ASCO Post! The article highlights our groundbreaking study, which reveals how a specific sequence of therapies can significantly improve survival rates for patients with relapsed/refractory T-and NK-cell lymphomas. By leveraging global data from PETAL, we are moving closer to refining treatment strategies and providing new hope for patients with limited treatment options
Read MoreWe are excited to share that PETAL Consortium is featured in the ASCO Post! The article highlights our groundbreaking study, which reveals how a specific sequence of therapies can significantly improve survival rates for patients with relapsed/refractory T-and NK-cell lymphomas. By leveraging global data from PETAL, we are moving closer to refining treatment strategies and providing new hope for patients with limited treatment options
PETAL Research Featured in Mass General Brigham News
Our recent publication in the British Journal of Haematology has been featured by
Mass General Brigham. The news release underscores the PETAL Consortium's
innovative and impactful research in guiding personalized treatment strategies for
relapsed and refractory T- and NK-cell lymphomas.
Read MoreOur recent publication in the British Journal of Haematology has been featured by
Mass General Brigham. The news release underscores the PETAL Consortium's
innovative and impactful research in guiding personalized treatment strategies for
relapsed and refractory T- and NK-cell lymphomas.
Forecasting Optimal Treatments in Relapsed/Refractory Mature T- and NK-Cell Lymphomas - The PETAL Consortium's latest paper published in the British Journal of Haematology.
Read More
We are thrilled that our clinical researcher Caroline MacVicar has been accepted to and plans on attending dimedical school at Uniformed Services University (USU).Congratulations!
Caroline MacVicarWe are delighted to congratulate Dhruv Mistry a key PETAL team member on earning
his M.B.B.S. degree. We cannot wait to see his career unfold.
PETAL Publications
We are excited to announce that our paper, Forecasting optimal treatments in
relapsed/refractory mature T- and NK-cell lymphomas, has been published in the
British Journal of Haematology. This collaborative work leverages machine learning
and genomic insights to predict the most effective treatment regimens for aggressive
T-and NK-cell lymphomas.Read More
April 2025
PETAL Highlights
March 2025
PETAL Highlights
PETAL Consortium at the TCLF 2025 shared their ongoing projects and work through
multiple compelling oral and poster presentations.
PETAL Publication
T-cell Lymphoma Forum (TCLF) 2025
The PETAL Consortium and Jain Lab T-cell lymphoma program was invited to give 3 oral
presentations and 2 poster presentation on their latest ongoing work on the global PETAL consortium
- an incorporation of novel machine learning strategies to estimate patient outcomes for peripheral T-
cell lymphoma.

Is There a Role for MRD in Predicting Outcome Post
Transplant? Presented by Dr. Salvia Jain.
Dr. Salvia JainA. Oral Presentations

PETAL Consortium: Transforming the Tc-Cell Lymphoma
Research Landscape Presented by Forum Bhanushali
Forum Bhanushali
Integrative Analysis of Histone Modifications and 3D
Chromatin Organization Reveals Altered Epigenetic
Landscapes across T-Cell Lymphoma Subtypes Presented
by Caroline MacVicar
Caroline MacVicarB. Poster presentations


February 2025
PETAL highlights
PETAL Publications


January 2025
PETAL Highlights
Blood Cancers Today spoke with researchers from the Salvia Jain Lab to learn more
about the goals and initiatives of the PETAL Consortium. Leora Boussi, MD, Angela
Koh, and Jessy Xinyi Han discuss their study of a novel scoring system using one of
the largest international global cohorts of 925 patients with relapsed or refractory
mature T-cell and NK-cell lymphomas.Read More
December 2024
PETAL Highlights
PETAL Publications
American Society of Haematology Conference 2024
The PETAL Consortium and Jain Lab T-cell lymphoma program was invited to give 3 oral
presentations and 2 poster presentation on their latest ongoing work on the global PETAL consortium
- an incorporation of novel machine learning strategies to estimate patient outcomes for peripheral T-
cell lymphoma.
A. Oral presentations
B. Poster presentations

November 2024
PETAL highlights
The BROAD Institute joins PETAL as a genomics collaborator, bringing cutting-edge expertise to the consortium.
October 2024
American Society of Hematology (ASH) News
Four abstracts were selected at the annual meeting to be held in San Diego in December by several members of the Jain Lab oral/poster presentations.
Several members of the group received ASH abstract achievement awards.
PETAL News
The first manuscript of the PETAL Consortium titled Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: Results was accepted for publication in Blood Advances.
The PETAL consortium developed a new prognostic model [PIRT Score] for patients with relapsed and refractory T cell lymphoma. This prognostic model is now free for use by qualified health care professionals on the PETAL consortium website.Read more
September 2024
Alexandra LenartAlexandra Lenart
Members of the Jain Lab led by Alexandra Lenart participated in the Mass General
Cancer Center Eversource 5K Walk-Run and collectively raised over $5000 to support
the Cancer Center.
August 2024
Daiichi Sankyo, Inc
The Jain Lab was awarded an educational grant by Daiichi Sankyo, Inc for building
novel machine learning approaches to estimate patient survival outcomes.
July 2024
Makoto lwasaki
Makoto Iwasaki, MD, PhD has received the ASH Global Research Award from the
American Society of Hematology (ASH) with the support of Caroline MacVicar to
support his work in developing machine learning models to T-cell lymphoma
outcomes.
June 2024
The Jain Lab T-cell lymphoma program was invited to give two oral presentations on their
global PETAL consortium and incorporation of novel machine learning strategies to
estimate patient outcomes for peripheral T-cell lymphoma. In addition, poster presentations
were given by members of the lab and are listed below. We are extremely proud of our team
for their amazing accomplishments!
A. Oral Presentations
Salvia Jain
Global patterns of care in PTCL, Presented by: Salvia Jain
Mark Sorial
Incorporation of Novel Causal Inference Methods to Define Impact of Therapy Sequences in Relapsed and Refractory Mature T- and NK-Cell Neoplasms: A Global Study of the PETAL Consortium, Presented by: Mark N Sorial
B. Poster Presentations
Sean McCabe
Integrated Omics to Dissect the Landscape in Chemosensitive and Refractory Extranodal Natural-Killer T-Cell Lymphoma (ENKTCL): A Global Study of the PETAL (PEripheral T-Cell Lymphoma) Consortium, Presented by: Sean M McCabe
Caroline MacVicar
Integrative analysis of 3D chromatin organization reveals regulation mechanisms in angioimmunoblastic T-cell lymphoma, Presented by: Caroline MacVicar
Josie Ford
Molecular Residual Disease Detection via CAPP-Seq in Patients with PTCL Undergoing Autologous Stem Cell Transplantation, Presented by: Josie Ford
Delineating the mechanism of fragility at BCL6 breakpoint region associated with translocations in diffuse large B cell lymphomaRead more
May 2024
Mark Sorial has received funding from SecuraBio to conduct work related to machine
learning to analyze patient outcomes of T and NK neoplasms
April 2024
Shambhavi Singh, MD, PhD was selected as a recipient of the 2024 ASH Next Generation of Research Scientists Honors Award
March 2024
Our clinical research coordinators Ronald Nemec, Josie Ford, and Sean McCabe have been accepted and are planning on attending medical school at Brown University, University of Connecticut, and Cornell University
January 2024
Delineating the mechanism of fragility at BCL6 breakpoint region associated with translocations in diffuse large B cell lymphomaRead more
KLRG1 Cell Depletion As A Novel Therapeutic Strategy In Patients With Mature T-cell
lymphoma SubtypesRead more
Makoto Iwasaki was awarded the Takeda Science Foundation Research Fellowship in
Japan.
December 2023
Makoto Iwasaki was awarded the Uehara Memorial Foundation’s Overseas Research Fellowship in Japan.
Novel Causal Inference Method Estimates Treatment Effects of Contemporary Drugs in a Global Cohort of Patients with Relapsed and Refractory Mature T-Cell and NK-Cell NeoplasmsRead more
Impact of Therapy Sequence on Survival Outcomes Among Patients with Relapsed or Refractory Mature T and NK Cell Neoplasms: A Global Retrospective Cohort StudyRead more
October 2023
Min Jung Koh was selected as a recipient of American Society of Hematology (ASH) Abstract Achievement Award.
September 2023
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphomaRead more
May 2023
Maria Jose Fernandez Turizo has been selected as a recipient of the ASH Minority Resident Hematology Award Program.
February 2023
Real-World Experience of Combined Treatment with Azacitidine and Romidepsin in Patients with Peripheral T-Cell LymphomaRead more



